Maria Bondesson Bolin
Department(s):
School of Integrated Sciences, Sustainability, and Public Health
School of Integrated Sciences, Sustainability, and Public Health
Title(s):
Professor
Presidential Professor
Office Location
HSB 313
Email
ebond5@uis.edu
Research
  • Developmental Toxicology: Using zebrafish as a model system, we investigate the effects of environmental pollutants on embryonic development, with a focus on neuronal, vascular, and skeletal systems.
  • Endocrine Disruption: Screening for chemical pollutants that alter hormone levels or disrupt hormone signaling pathways, using genetically engineered zebrafish models or cell-based methods.
  • Molecular Toxicology: Applying -omics methodologies (transcriptomics, lipidomics, proteomics) to decipher the molecular mechanisms altered by exposure to environmental pollutants.


Publications

Select Publications

  1. Mesmar F, Muhsen M, Ibraheem Farooq, Tourigny JP, Tennessen JM, and Bondesson M. Exposure to the pesticide tefluthrin causes developmental neurotoxicity in zebrafish. bioRxiv 10.1101/2024.05.28.596249v1 https://doi.org/10.1101/2024.05.28.596249
  2. Mesmar F, Muhsen M, Mirchandani R, Tourigny JP, Tennessen JM, and Bondesson M. The herbicide acetochlor causes lipid peroxidation by inhibition of glutathione peroxidase activity. Toxicological Sciences 2024 202 (2): 302¿313. PMID: 39240656 https://doi.org/10.1093/toxsci/kfae113
  3. Bianchi E, Bhattacharya B, Bowling AJ, Pence HE, Mundy PC, Jones G, Muriana A, Grever WE, Pappas-Garton A, Sriram S, LaRocca J, Bondesson M*. Applications of zebrafish embryo models to predict developmental toxicity for agrochemical product development. Journal of Agricultural and Food Chemistry 2024 72(32): 18132-18145. PMID: 39087946 https://pubs.acs.org/doi/10.1021/acs.jafc.4c00970
  4. Tian C, Cai H, Ao Z, Gu L1, Li X, Niu V, Bondesson M, Gu M, Guo F. Engineering human midbrain organoid microphysiological systems to model prenatal PFOS exposure. Science of the Total Environment 2024 947:174478. PMID: 38964381 https://doi.org/10.1016/j.scitotenv.2024.174478
  5. Knudsen T, Saili K, Franzosa J, Baker N, Spencer R, Tal T, Kleinstreuer N, Heinonene T, Ellis-Hutchings R, Vargesson N, Bondesson M. Disruption of VEGFR signaling leading to developmental defects. AOP No. 43 in the AOP-Wiki platform. OECD Series on Adverse Outcome Pathways No. 31 2023. PMID: 37211341 https://dx.doi.org/10.1787/c1116a35-en
  6. Thrikawala S, Mesmar F, Bhattacharya B, Muhsen M, Mukhopadhya S, Flores S, Upadhyay S, Vergaras L, Gustafsson JA, Williams C, Bondesson M. Triazole fungicides induce adipogenesis and repress osteoblastogenesis in zebrafish. Toxicological Sciences 2023 193(2):119-130. PMID: 36951524 https://doi.org/10.1093/toxsci/kfad031
  7. Karim S, Hao R, Pinto C, Gustafsson JÅ, Grimaldi M, Balaguer P, Bondesson M. Bisphenol A analogues induce a feed-forward estrogenic response in zebrafish. Toxicology and Applied Pharmacology 2022 455:116263. PMID: 36195136 https://doi.org/10.1016/j.taap.2022.116263
  8. Gorelick D, Pinto CL, Hao R, Karim S, Bondesson M. Use of reporter genes to analyze estrogen response: the transgenic zebrafish model. Methods Mol Biol. 2nd Edition 2022 2418:173-185 (1st edition 2016 1366:315-25). PMID: 35119666 https://doi.org/10.1007/978-1-0716-1920-9_11


List of publications in PubMed: https://www.ncbi.nlm.nih.gov/myncbi/maria.bondesson%20bolin.1/bibliography/public/


List of publications in Google Scholars: 08/27/2025: https://scholar.google.com/citations?user=9DSdzygAAAAJ&hl=en&oi=ao

Teaching
  • MPH449/CHE465 Environmental Toxicology (from Fall 2025)
  • Biotechnology (from Spring 2026)